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KMID : 1211620120070020149
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Journal of the Korean Society of Physical Medicine
2012 Volume.7 No. 2 p.149 ~ p.155
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Analysis of Correlations among Bone Mineral Density, Serum Lipid Levels, and Cognitive Function in the Elderly with Dementia
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Kim Soo-Han
Kim Ji-Sung
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Abstract
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Purpose: The purpose of this study was to analyze the correlations among bone mineral density(BMD), serum lipid levels, and cognitive function in the elderly with dementia.
Methods: We recruited seventy elderly with dementia(men=35, women=35) to participate in the Korean mini mental state examination(K-MMSE). Their T-scores and serum lipid levels were analyzed for correlation analysis.
Results: The results of this study showed that there are significant correlations between cognitive function and three factors BMD, low-density lipoprotein cholesterol(LDL-C) level, and total cholesterol(TC) level. The cognitive function scores increased proportionally with BMD but were inversely proportional to LDL-C and TC levels. There were no significant relations among cognitive function, high-density lipoprotein cholesterol(HDL-C) level, and triglyceride(TG) level.
Conclusion: These results indicate that there is a direct proportionality between cognitive function and BMD and inverse proportionalities between cognitive function and LDL-C level and between cognitive function and TC level. Therefore, these levels can be indices for preventing and predicting dementia.
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KEYWORD
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Dementia, Cognitive function, Bone mineral density, Serum lipid levels
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